Thank you, for being one of the 100 fighters, if you have not join yet, please signup here
With your support, NF2 BioSolutions is launching and supporting many different novel therapies approaches. We are supporting several methods in parallel and we believe in a multi-modal approach since we don’t know yet what is going to work in the future. Of all the therapy approaches we are supporting, some have the goal of killing existing tumors, some have the goals of stopping tumor growth, and some search to stop new tumors from forming.
Today we need you to complete our fundraiser for jumpstarting the Adoptive Cell Therapy with Tumor-infiltrating Lymphocytes to tackle the NF2 tumors, the goal is for each fighters to raise/donate $700. Please signup here now to join this new challenge
This approach is a type of novel immunotherapy that has been used and it’s effective in other cancers. The cost of the first phase of this project is $106,000. On Monday 28th of February, we started to fundraise and raised $35,000, we still need $71,000. If 100 fighters raise $700 each, we will reach our goal. More details below:
Why are we fundraising? (Text you can use in your communications):
“People with NF2 have a genetic mutation that results in growth of multiple tumors in the nervous system. They develop schwannomas, meningiomas and ependymoma tumors which first appear during childhood. These tumors cause deafness, pain, sensory/motor dysfunction, and eventually death through compression of the brain stem, spinal cord, and nerves. Effective chemotherapy is non-existent. Surgery and radiation can be more damaging as the tumors themselves. Most patients end up with nerve damage that leads to deafness, blindness, chronic severe pain, loss of vocal cord and motor function. The paucity of therapeutic options makes the treatment of NF2 tumors a major unmet medical need.
NF2 Biosolutions is putting the best labs and best minds in the race to tackle the cruelty of NF2. We continue nonstop at evaluating new approaches and techniques to tackle NF2.
So far we support four different novel therapy approaches. Since we don’t know yet if these approaches that are demonstrating promise in the lab will ultimately work as well in a human, we don’t want to focus on just one area. We want to continue to onboard new labs and researchers with novel ideas and medical approaches. Today we need to jumpstart the Adoptive Cell Therapy with Tumor-infiltrating Lymphocytes to tackle the NF2 tumors. TILs are a type of immune cell that has moved from the blood into a tumor. Tumor-Infiltrating Lymphocytes (TILs) can recognize and kill cancer cells. In cancer therapy, Tumor-Infiltrating Lymphocytes are removed from a patient’s tumor, grown in large numbers in a laboratory, and then given back to the patient to help the immune system kill the cancer cells.
Objectives of this project:
In this project, we aim to investigate the potential for TIL immunotherapy for NF2 associated tumors by:
- Developing a method to isolate and expand TILs from freshly resected NF2 associated tumors
- Determining if these expanded TILs have anti-tumoural properties on NF2 associated tumor cells in vitro
Cost: $106,000. It requires salary costs for 4 technicians to carry out the experimental work and material cost. These costs reflect the high cost of consumables to generate and analyze TIL.
Research Lab: Principal Investigator: Omar Pathmanaban, Manchester Academic Health Science Centre. Co-applicants: Claire O’Leary, Gareth Evans, Richard Edmondson, Federico Roncaroli, Fiona Thistlewaite, Andrew King, University of Manchester, Manchester, UK.
Different ways to fundraise:
1. Fundraiser Webpage to share:
You can share this fundraiser page https://donorbox.org/one-hundred-nf2-fighters by email or on social media but don’t forget to tell them to type in the form your name (fundraiser fighter) so we will know that the donation is toward your $1000 goal. We will let you know when someone donated.
Or do you want your private fundraiser webpage? Like this one for example : https://donorbox.org/100-fighters-challenge-robyn ? With your own $ meter goal. Please request it to Gilles at email@example.com
2. Create your Facebook fundraiser, it is easy:
See the fundraiser of Matt as an example: https://www.facebook.com/donate/291443865699398/10225206951190654/
You can also add the “Lion 100 fighters” image on your fb fundraiser to drag more the attention. Here is the image that you can download and add to your fundraiser.
3. Race/Run virtual 5K: make your friends and family signup for this health challenge. (20$ signed up)
3. Find items to auction and create an auction on Facebook
4. Pampered Chef sales
. You can run your own pampered Chef product sales to your friends and family network, 20% of the sales will go to NF2 BioSolutions. If you are interested contact Erin Stuckey firstname.lastname@example.org (210) 753-6449 and tell her you want to raise funds for NF2 BioSolutions. Erin will guide you in making this event successful.
5. Card Party Event Fundraiser
In Michigan, people are fond of playing Euchre (a trick taking game with a trump, played by four players in teams of two) but this would work with any similar card game. Terri Rausch, board member of NF2 BioSolutions is explaining to us how to run such an event, Click here for all the info.
6. Ice Cream Social Fundraiser Event