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With your support, NF2 BioSolutions has launched and supported many novel therapy approaches. We are supporting several methods in parallel as we believe in a multi-modal approach since we don’t know yet what will work in the future. Of all the therapy approaches we are supporting, some have the goal of killing existing tumors, some have the goal of stopping tumor growth, and some search to stop new tumors from forming.
Today we need you to complete our fundraiser for jumpstarting the IND-Enabling Rat Toxicology Study, part of the IND Phase of the preparation for clinical trials for the Gene Therapy project at Nationwide Children’s Hospital.
The goal is for each fighter to raise/donate $1,000. Please sign up here now to join this new challenge
This approach is a type of novel immunotherapy that has been used and it’s effective in other cancers. The cost of this study is $400,000. More details below:
Why are we fundraising? (Text you can use in your communications):
The groundbreaking Gene Therapy led by Dr. Meyer at Nationwide Children’s Hospital focuses on restoring the Merlin protein in the NF2 gene by using an AAV9 viral construct as a delivery mechanism. The efficacy of this construct is currently undergoing testing. Testing is also ongoing in the KO (Knockout) mouse and xenograft mouse models using intratumoral injections. We successfully showed the expression of Merlin in tumor cells, accompanied by reduced tumor growth in the xenograft model.
Pre-IND (Investigational New Drug) documents explaining our clinical trial plan are being prepared to be submitted to the FDA.
The toxicology study is the vital piece of the puzzle that helps ensure the safety and efficacy of the therapy before it reaches patients. It’s a critical checkpoint on our path toward finding a cure for NF2. With your help, we can take this important step and change lives.
Cost: $400,000. It covers the cost of the Rat Toxicology Study which is part of the Investigational New Drug (IND)
Research Lab: Dr. Katrin Meyer leads this project in her lab at Nationwide Children’s Hospital.
Different ways to fundraise:
1. Fundraiser Webpage to share:
You can share this fundraiser page Giving Tuesday 2023 – Gene Therapy for NF2, by email or on social media, but don’t forget to tell them to type in the form your name (fundraiser fighter) so we will know that the donation is toward your $1000 goal. We will let you know when someone donates.
Or do you want your private fundraiser webpage? With your own $ meter goal. Please request it by filling out this form: https://forms.gle/Jsmtc1aRJyB9Tg5x8
2. Create your Facebook fundraiser, it is easy:
Create your own Facebook donation campaign, and post on your Facebook wall with your fundraiser goal. Go here for instructions on how to set it up.
You can also have personalized images on your FB fundraiser to draw more attention. Fill out this form to get your own!
3. Find items to auction and create an auction on Facebook
Here is a simple How-to video where Chantelle Nobis explains how she created her auction on Facebook and raise funds. Do not hesitate to contact Chantelle at chantelle@nf2biosolutions.org
4. Pampered Chef sales
. You can run your pampered Chef product sales to your friends and family network; 20% of the sales will go to NF2 BioSolutions. If you are interested, contact Erin Stuckey erin.stuckey78@gmail.com (210) 753-6449 and tell her you want to raise funds for NF2 BioSolutions. Erin will guide you in making this event successful.
5. Card Party Event Fundraiser
In Michigan, people are fond of playing Euchre (a trick-taking game with a trump, played by four players in teams of two), but this would work with any similar card game. Terri Rausch, the board member of NF2 BioSolutions, is explaining to us how to run such an event, Click here for all the info.
6. Ice Cream Social Fundraiser Event
It is a social event for friends, family, and people impacted by NF to gather, eat ice cream, network, and have fun. You can do this by donating only, setting out a box and throwing in cash or checks. Here Terri is explaining how to run such an event.
